Dogs and cats commonly develop conditions of the gastrointestinal (GI) tract resulting in inflammation, erosions, and / or ulceration. These conditions may be primary in origin or present as a comorbidity associated with another disease process (e.g. kidney disease, liver disease, pancreatitis, etc.). GI protectants including antacids are commonly prescribed for dogs and cats with GI disorders, as these drugs decrease decrease gastric acid production and promote protective mechanisms of the GI mucosa. The inappropriate use of gastroprotectants and antacids can have adverse effects; As such adherence to the most current and evidence-based recommendations regarding their use is warranted. In this Specialty Update we report on 17 points - in sum and substance - regarding the use of gastroprotectants and antacids in dogs and cats, and discuss current recommendations as outlined in the ACVIM Consensus Statement on this topic. Discussion includes use of these drugs: - To prevent or manage glucocorticoid-associated GI ulcers or erosions - In critically ill or stressed animals - In patients with non-H. pylori Helicobacter - In the prevention and / or management of non-erosive gastritis, reflux esophagitis, pancreatitis, liver disease, and kidney disease - Including precautions and adverse effects of these drugs - Best drug options and effectiveness Running time: 15 mins Member Fee: $14.95; Free registration for Premium VetVine Membership subscribers: http://vetvine.com/article/181/evidence-based-update-subscriptions